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Mathematical modelling in tobacco control research

which tobacco use and tobacco control interventions operate.1 ,2 Acknowledging the complex drivers of tobacco use and related diseases, tobacco control researchers have become increasingly

interested in systems science methods.3 ,4

One approach used in systems science research is mathematical modelling which, broadly conceived, illustrates and attempts

to quantify how a system’s components are inter related and how outcomes of interest might be affected when a system undergoes

change.3 In tobacco control research, such models have been used to understand the future scope of disease burden,5 7 the potential effects of policies and regulations,8 10 and the economic consequences of interventions.11 13 However, there is currently no resource that provides an overview or synthesis of how these modelling techniques have been

developed and used in tobacco control. This gap limits the ability of researchers to learn
replica ray ban sunglasses from and improve on existing models.

Moreover, modelling approaches have been heterogeneous in their methods and even though they attempt to predict similar types

of outcomes (eg, lung cancer, quality adjusted life years), results have not been adequately synthesised, weakening their

ability to contribute to the evidence base for regulatory policy decisions. This review will address this gap by providing

a summary of modelling techniques that have been used in tobacco control research to predict tobacco related outcomes. It

will also propose a conceptual framework for grouping existing modelling studies by their objectives, which will serve as

the foundation for future analyses of these data.

This effort is intended to inform regulatory decision making. The Center for Tobacco Products at the US Food and Drug Administration

has expressed an interest in modelling
discount ray bans the impact of its policies.14 The results of this review will help decision makers at the national, state and local levels to gain a better understanding

of the scope, content and quality of existing modelling studies.

The Cochrane Collaboration provides rigorous guidelines for conducting systematic reviews.15 However, these guidelines were developed to inform systematic reviews that investigate the effectiveness of healthcare interventions.16 Thus, while the Cochrane approach to conducting systematic reviews will inform the methodology of this review,15 we
fake ray bans will also draw on guidelines from reviews that
cheap ray bans are specifically intended to inform policy and programme decision making.17 This protocol reports on recommended items to address in a systematic review protocol, in compliance with the preferred reportingArticles Connexes:


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